Research Articles
Comparative Method in Analytical Validation: A Guide for Researchers and Scientists
This article provides a comprehensive guide to the comparative method, a critical experiment in analytical method validation used to estimate systematic error or inaccuracy.
Evaluating Transferability of Optimized Force Field Parameters: Strategies for Computational Drug Discovery
This article provides a comprehensive framework for evaluating the transferability of optimized force field parameters in molecular simulations, a critical challenge in computational chemistry and drug discovery.
Accelerating Quantum Chemistry with Gaussian Process Surrogates: A Guide for Computational Researchers
This article provides a comprehensive overview of Gaussian Process (GP) surrogate models and their transformative potential in quantum chemistry calculations.
Surrogate-Based Optimization in Process Systems Engineering: A Guide for Biomedical Researchers
This article provides a comprehensive exploration of surrogate-based optimization (SBO) techniques, tailored for researchers, scientists, and professionals in drug development and biomedical engineering.
Surrogate Models in Expensive Black-Box Optimization: Accelerating Discovery in Biomedicine and Beyond
This article explores the transformative role of surrogate models in tackling computationally expensive black-box optimization problems, with a special focus on applications in drug development and biomedical research.
Comparative Analysis of SPE Cartridges for Complex Matrices: A Strategic Guide for Biomedical Researchers
This article provides a comprehensive, application-focused guide for researchers and drug development professionals on selecting and optimizing Solid Phase Extraction (SPE) cartridges for diverse sample matrices.
Portable vs. Laboratory Instruments in 2025: A Performance Comparison for Research and Diagnostics
This article provides a comprehensive performance comparison between portable and laboratory instruments for researchers, scientists, and drug development professionals.
Sequential Simplex Optimization: A Practical Guide for Multi-Factor Optimization in Drug Development
This article provides a comprehensive guide to Sequential Simplex Optimization, a powerful multivariate chemometric tool for efficiently optimizing multiple factors in complex systems.
Flow Injection Analysis LC-MS Optimization: A Complete Guide for Robust Method Development
This article provides a comprehensive guide to optimizing Flow Injection Analysis (FIA) for Liquid Chromatography-Mass Spectrometry (LC-MS).
UV-Vis Method Validation for Regulatory Compliance: A Practical Guide for Pharmaceutical QC
This article provides a comprehensive framework for developing and validating UV-Vis spectrophotometric methods to meet stringent regulatory standards in pharmaceutical quality control.