Research & Methodologies

Explore breakthrough studies, advanced techniques, and peer-reviewed insights in analytical chemistry

Research Articles

From Green to White: The Evolution of Sustainable Analytical Chemistry Principles in Pharmaceutical Research

This article explores the transformative evolution of sustainable practices in analytical chemistry, tracing the journey from foundational Green Analytical Chemistry (GAC) principles to the holistic framework of White Analytical Chemistry...

Charles Brooks
Nov 27, 2025

From Prescriptive Checklists to Lifecycle Management: The Evolution of Analytical Method Validation Protocols

This article traces the transformative journey of analytical method validation from its origins in prescriptive checklists to the modern, science- and risk-based lifecycle approach.

Andrew West
Nov 27, 2025

From Plant Extracts to Pharmaceuticals: The Historical Development and Modern Optimization of Extraction Freezing Methods

This article traces the historical development of extraction freezing methods from early food preservation applications to sophisticated pharmaceutical and biomedical extraction techniques.

Aubrey Brooks
Nov 27, 2025

Electrospray Ionization Mass Spectrometry: From Nobel Prize Discovery to Modern Drug Development

This article explores the transformative journey of electrospray ionization mass spectrometry (ESI-MS), a Nobel Prize-winning technology that revolutionized the analysis of biological macromolecules.

Madelyn Parker
Nov 27, 2025

From Theory to Therapy: How Memristor Technology is Revolutionizing Analytical and Biomedical Devices

This article explores the transformative journey of the memristor from a theoretical concept to a cornerstone of next-generation analytical and biomedical devices.

Hazel Turner
Nov 27, 2025

Analytical Method Transfer Protocol: A Comprehensive Guide for Seamless Laboratory Transitions

This article provides a complete guide to analytical method transfer (AMT) for researchers, scientists, and drug development professionals.

Emma Hayes
Nov 27, 2025

Peak Purity Testing with PDA and MS: A Comprehensive Guide for Robust Analytical Methods

This article provides researchers, scientists, and drug development professionals with a complete guide to peak purity assessment, a critical technique for ensuring accurate quantification and method specificity in HPLC.

Nora Murphy
Nov 27, 2025

Intermediate Precision Testing Between Analysts: A Complete Guide for Robust Analytical Methods

This article provides a comprehensive guide to intermediate precision testing with a specific focus on variability between analysts, a critical component of analytical method validation in pharmaceutical development and quality...

Elizabeth Butler
Nov 27, 2025

Linearity and Range Validation in Analytical Methods: A Comprehensive Guide for Robust Method Development

This article provides a complete guide to linearity and range validation, essential parameters in analytical method validation for pharmaceuticals and bioanalysis.

Adrian Campbell
Nov 27, 2025

LOQ and Signal-to-Noise Ratio: A Complete Guide for Robust Bioanalytical Method Validation

This article provides a comprehensive guide to the Limit of Quantitation (LOQ) and its critical relationship with the signal-to-noise (S/N) ratio, tailored for researchers and drug development professionals.

Lucy Sanders
Nov 27, 2025

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